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A pooled analysis of 2 studies using rucaparib for the treatment of patients with recurrent high-grade ovarian cancer supported the approved starting dose of 600 mg twice daily. Read More ›

A global phase 3 randomized study is currently enrolling patients with stage III or IV high-grade nonmucinous epithelial ovarian cancer to assess the efficacy of an investigational anti–PD-1 humanized monoclonal antibody plus standard of care as first-line treatment and maintenance. The primary outcome measure is progression-free survival. Read More ›

Clinical Data on First-Line Maintenance Therapy in Ovarian Cancer
Amina Ahmed, MD, Paula Anastasia, RN, MN, AOCN and Ali McBride, PharmD, critically review the clinical trial data supporting the use of PARP inhibitors and bevacizumab as first-line maintenance therapy in ovarian cancer. Read More ›

Pembrolizumab (Keytruda) in combination with chemotherapy demonstrated a statistically significant and clinically meaningful improvement in progression-free survival (PFS) compared with chemotherapy alone as a first-line treatment for patients with metastatic triple-negative breast cancer (TNBC) whose tumors express PD-L1. Read More ›

Early locoregional therapy with surgery and radiation does not improve overall survival (OS) in women with newly diagnosed stage IV breast cancer and an intact primary tumor compared with systemic therapy alone, according to the results of the randomized ECOG-ACRIN E2108 phase 3 clinical trial. The results were presented by lead investigator Seema A. Khan, MD, FACS, MPH, Co-Leader, Lynn Sage Comprehensive Breast Center, Northwestern Memorial Hospital, Chicago, IL, at the plenary session of the ASCO 2020 virtual annual meeting. Read More ›

For decades, healthcare professionals have worked diligently to teach individuals that screening is a valuable tool for preventing and detecting cancer. This has not been an easy mission, and nurses and physicians have had to debunk the myths, bias, and misinformation that deter patients from getting screened annually or according to specific guidelines set forth by organizations such as the Centers for Disease Control and Prevention (CDC) and the American Cancer Society (ACS). Although clinicians have been telling their patients—and the population at large—not to put off cancer screening because it saves lives, when the COVID-19 pandemic hit in March of this year, the dialogue changed. Read More ›

Medical practices entered a strange new world of patient safety requirements during the COVID-19 pandemic, and life will never again be the same. Regardless of size or specialty, all medical practices face significant challenges to protect their patients, community, and staff by reducing the risk of spreading the COVID-19 virus, while simultaneously maintaining their financial viability. Read More ›

As oncology management professionals, the sentiment is never lost that people are our strongest asset. The proficiency of a practice’s front-line staff can affect the efficacy of treatment, support the initiatives of professional organizations, and greatly influence the mood and mindset of patients. Therefore, as we continue to navigate through the ever-changing healthcare environment, it is critical to take the necessary steps to support those who are critical to the care of our patients. Read More ›

Vaping devices, also known as e-cigarettes, are the new epidemic among young people in the United States, according to Nancy Sayegh-Rooney, RN, a lung nurse navigator on Staten Island, NY, and a Certified Tobacco Treatment Specialist who educates students in middle school and high school about the dangers of vaping. Read More ›

The current state of our nation has resulted in an ever-present focus on the COVID-19 virus. This is fully warranted given its indescribable impact on the psychological, emotional, and financial well-being of individuals and communities worldwide. As our society tunes in daily to a barrage of pandemic casualty data, a number of smokers have expressed increased interest in assistance with smoking cessation. This observation of increased “readiness to quit” is likely influenced by reports concerning patients infected with COVID-19 who smoke having poorer outcomes than those who do not. Read More ›

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