Miami Breast Cancer Conference

Tucatinib and neratinib show encouraging activity in patients with advanced breast cancer and central nervous system metastases. Read More ›

Alterations in CDK and PI3K pathways are frequent in breast cancer brain metastases; could targeting these genetic alterations lead to improved survival? Read More ›

New research reveals that brain metastases harbor distinct clinically actionable genetic alterations compared with primary tumors and extracranial metastases. Read More ›

An analysis of the phase 3 ExteNET clinical trial shows that extended adjuvant therapy with neratinib leads to better outcomes among patients with earlystage HER2-positive breast cancer after trastuzumab-based therapy, but only when diarrhea does not lead to dropout. Read More ›

DS-8201 yields exciting results in HER2-positive, TDM-1 resistant, or refractory metastatic disease, but providers should remain vigilant about the incidence of interstitial lung disease. Read More ›

With several new therapies on the horizon for HER2-positive metastatic breast cancer, tucatinib stands out for its notable activity in patients with brain metastases. Read More ›

Treatment options continue to emerge for patients with HER2-positive advanced breast cancer, with some generating more buzz than others. Read More ›

Should all patients with HER2-positive tumors between 1 cm and 2 cm receive neoadjuvant chemotherapy? Experts weigh in. Read More ›


Central nervous system objective responses were observed in patients with HER2-positive metastatic breast cancer treated with neratinib in 3 separate clinical trials. Read More ›

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