Clinical trial recruitment and retention remain challenges in the quest to bring innovative therapies to all patients in need. In oncology, therapies continue to evolve, yet researchers are frequently faced with low trial participation, particularly among minority groups.
Oncology Practice Management (OPM) is dedicated to providing comprehensive information aimed at eliminating health disparities and improving access to therapies for people from all populations, including racial and ethnic minorities, people with limited access to healthcare due to lack of financial resources, and people living in rural communities.
This feature in OPM aims to provide ongoing lists of phase 2 or 3 clinical trials based in the United States that are actively recruiting. This issue is focused on prostate cancer because September is prostate cancer awareness month. Healthcare practitioners may use this listing in discussions with their patients to encourage enrollment. As the National Comprehensive Cancer Network has stated, “The best management of any cancer patient is in a clinical trial.”
These clinical trial listings can be found at www.ClinicalTrials.gov.
- MR-Guided Cryoablation of Prostate Bed Recurrences
- ClinicalTrials.gov Identifier: NCT01727284
- Sponsor: Mayo Clinic
- MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)
- ClinicalTrials.gov Identifier: NCT06150417
- Sponsor: Case Comprehensive Cancer Center
- T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine M9241 in Localized High- and Intermediate-Risk Prostate Cancer Treated With Androgen Deprivation Therapy
- ClinicalTrials.gov Identifier: NCT05361798
- Sponsor: National Cancer Institute (NCI)
- MRI-Guided Cryoablation for Focal Native Prostate Cancer
- ClinicalTrials.gov Identifier: NCT04797039
- Sponsor: Mayo Clinic
- High-Dose Brachytherapy Boost With Stereostatic Body Radiation Therapy to Intermediate or Higher Risk Prostate Cancer
- ClinicalTrials.gov Identifier: NCT05754580
- Sponsor: University of Nebraska
- M9241 in Combination With Docetaxel in Adults With Metastatic Castration Sensitive and Castration Resistant Prostate Cancer
- ClinicalTrials.gov Identifier: NCT04633252
- Sponsor: National Cancer Institute
- Neoadjuvant SGLT2 Inhibition in High-Risk Localized Prostate Cancer
- ClinicalTrials.gov Identifier: NCT04887935
- Sponsor: Washington University School of Medicine
- PSMA-Based 18F-DCFPyL PET/CT and PET/MRI Pilot Studies in Prostate Cancer
- ClinicalTrials.gov Identifier: NCT03232164
- Sponsor: University of Wisconsin, Madison
- Men at High Genetic Risk for Prostate Cancer
- ClinicalTrials.gov Identifier: NCT03805919
- Sponsor: National Cancer Institute
- 99mTc-PSMA-I&S Biodistribution in Patients With Prostate Cancer
- ClinicalTrials.gov Identifier: NCT04857502
- Sponsor: Jonsson Comprehensive Cancer Center
- MRI/Ultrasound Fusion Guided Prostate Cryotherapy (FIPC)
- ClinicalTrials.gov Identifier: NCT02381990
- Sponsor: Urological Research Network, LLC
- Determination of Baseline Levels for Prostate Cancer-Derived Extracellular Vesicles Following Local Treatment of Prostate Cancer
- ClinicalTrials.gov Identifier: NCT06326216
- Sponsor: Mayo Clinic
- Evaluation of the Impact of Empty Versus Full Bladder in Patients With Prostate Cancer, RELIEF Trial
- ClinicalTrials.gov Identifier: NCT06037863
- Sponsor: Mayo Clinic
- Prostate Cancer Diagnosis by Multiparametric Ultrasound (Wholemount)
- ClinicalTrials.gov Identifier: NCT05336786
- Sponsor: Thomas Jefferson University
- Detection of Prostate Cancer Using Voided Urine
- ClinicalTrials.gov Identifier: NCT04788277
- Sponsor: Thomas Jefferson University
- To Evaluate If Green Tea Can Be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring
- ClinicalTrials.gov Identifier: NCT04597359
- Sponsor: ECOG-ACRIN Cancer Research Group
- Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy
- ClinicalTrials.gov Identifier: NCT04646434
- Sponsor: Roswell Park Cancer Institute
- Internet-Based Lifestyle Intervention (iLIVE) to Eradicate Obese Frailty in Prostate Cancer Survivors (iLIVE)
- ClinicalTrials.gov Identifier: NCT06011499
- Sponsor: OHSU Knight Cancer Institute
- Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer
- ClinicalTrials.gov Identifier: NCT03772834
- Sponsor: MD Anderson Cancer Center
- Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer
- ClinicalTrials.gov Identifier: NCT02960087
- Sponsor: Canadian Cancer Trials Group
- CyberKnife Dose Escalation Prostate Cancer Trial (CK-DESPOT)
- ClinicalTrials.gov Identifier: NCT03822494
- Sponsor: Crozer-Keystone Health System
- RecoverPC: Relugolix vs GnRH Agonist in Quality of Life
- ClinicalTrials.gov Identifier: NCT05765500
- Sponsor: Dana-Farber Cancer Institute
- Imaging Studies to Check the Local Response of Prostate Cancer to Radiation Therapy
- ClinicalTrials.gov Identifier: NCT01834001
- Sponsor: National Cancer Institute
- Profiling of Radiological Factors in Treatment and Outcomes in Prostate Cancer
- ClinicalTrials.gov Identifier: NCT03354416
- Sponsor: National Cancer Institute
- Quality of Life in Patients With Clinically Localized Prostate Cancer Treated With Radiosurgery (PR-PROS)
- ClinicalTrials.gov Identifier: NCT01766492
- Sponsor: Georgetown University
- Collection of Blood From Patients With Prostate Cancer
- ClinicalTrials.gov Identifier: NCT00923221
- Sponsor: National Cancer Institute
- Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment Prostate Cancer
- ClinicalTrials.gov Identifier: NCT06369610
- Sponsor: Mayo Clinic
- Active Surveillance for Cancer of the Prostate (ASCaP)
- ClinicalTrials.gov Identifier: NCT00949819
- Sponsor: Jonsson Comprehensive Cancer Center
- DeADT - Living Well With Prostate Cancer (DeADT-LW)
- ClinicalTrials.gov Identifier: NCT06199986
- Sponsor: University of Michigan
- The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
- ClinicalTrials.gov Identifier: NCT05926102
- Sponsor: VA Office of Research and Development
- Non-Invasive Biomarkers in Prostate Cancer Disease Management
- ClinicalTrials.gov Identifier: NCT06144619
- Sponsor: H. Lee Moffitt Cancer Center and Research Institute
- Nivolumab in Biochemically Recurrent dMMR Prostate Cancer
- ClinicalTrials.gov Identifier: NCT04019964
- Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
