Dual Immune Checkpoint Inhibitors in Advanced Cutaneous Melanoma

Sanjiv S. Agarwala, MD
Professor
Temple University School of Medicine
Philadelphia, PA

Dr Sanjiv Agarwala reviews data for first-line immunotherapy with nivolumab plus relatlimab demonstrating significantly improved progression-free survival over monotherapy, and a high pathologic complete response rate with this combination in the neoadjuvant setting, in patients with advanced melanoma. He also reviews data from the CheckMate-067 study showing durable 6.5-year overall survival with first-line nivolumab plus ipilimumab in patients with advanced melanoma.

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