Leukemia





In April 2017, the FDA approved midostaurin (Rydapt) as the first tyrosine kinase inhibitor (TKI) for acute myeloid leukemia (AML) with a specific biomarker, FLT3 mutation, marking the introduction of targeted therapy for this notoriously difficult-to-treat type of leukemia. Read More ›

New results from the phase 3 QuANTUM-R trial showed that quizartinib, an oral, selective FLT3 inhibitor, significantly extended overall survival compared with chemotherapy in patients with relapsed/refractory acute myeloid leukemia (AML) and the FLT3-ITD mutation. Read More ›



On September 1, 2017, the FDA approved gemtuzumab ozogamicin (Mylotarg; Pfi­zer) for the treatment of adults with newly diagnosed CD33-positive acute myeloid leukemia (AML), as well as patients aged ≥2 years with relapsed or refractory CD33-positive AML. Read More ›


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