2020 Guide to Patient Support Services

Jazz Pharmaceuticals

Jazz Pharmaceuticals, through its JazzCares Program, offers patients support for its hematology/oncology drugs—Defitelio (defibrotide sodium), Erwinaze (asparaginase Erwinia chrysanthemi), and Vyxeos (daunorubicin and cytarabine) liposome (Table).

Defitelio is indicated for the treatment of patients with hepatic veno-occlusive disease associated with renal or pulmonary dysfunction after hematopoietic stem-cell transplantation.

Erwinaze is indicated as a component of a multiagent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia who are hypersensitive to Escherichia coli–derived asparaginase.

Vyxeos is indicated for adults with newly diagnosed therapy-related acute myeloid leukemia (AML) and for AML with myelodysplasia-related changes.


The JazzCares Program provides patients who are prescribed Defitelio, Erwinaze, or Vyxeos access to these medications through several financial assistance options. A patient assistance program is also offered for these 3 medications.


JazzCares Patient Assitance Program

Patients with no insurance may be able to receive their medication for free through JazzCares Patient Assitance Program for the respective medication. To be eligible for this program, the patient must:

  • Be a legal US resident
  • Have a valid prescription for indicated uses
  • Receive treatment on an outpatient basis
  • Have no insurance coverage or no medication coverage for Defitelio, Erwinaze, or Vyxeos.

In addition, the patient must provide proof of income, including ≥1 of these documents—a copy of a current federal income tax return, W-2 forms, yearly benefit statement (Social Security form 1099), pay stubs, and bank statements for 3 months for all earners in the household.

For more information about eligibility and assistance, please contact JazzCares specialists at 888-837-4397 for Defitelio or for Erwinaze, and at 855-589-9367 for Vyxeos.


Completed JazzCares application forms may be submitted by fax to 855-593-3955.

The application for JazzCares ­Patient Assistance Program for Vyxeos is available online. For more information call 833-533-5299.


Patient support programs

Defitelio (defibrotide sodium)
Patients with hepatic veno-occlusive disease associated with renal or pulmonary dysfunction after hematopoietic stem-cell transplantation
Patient support programs

Erwinaze (asparaginase Erwinia chrysanthemi)
Acute lymphoblastic leukemia for patients with hypersensitivity to Escherichia coli–derived asparaginase
Patient support programs

Vyxeos (daunorubicin and cytarabine) liposome
Adults with newly diagnosed therapy-related acute myeloid leukemia (AML) or AML with myelodysplasia-related changes
Patient support programs

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